A Topper Lift System for Pickups allows users to independently store wheelchairs in the truck bed. The system operates by hand-held remote only when cab door is open. It operates in conjunction with a wheelchair hoist and power truck seat lift. The topper lift system first lifts/lowers the cargo bed topper; the wheelchair hoist lifts the chair into/out of the bed; and the power seat lift rotates out the door for transfer to or from the chair. The system is designed for full-size, standard-bed pickups with 6-, 61/2- and 8-foot beds.